Table 2.
Patients with events according to immunosuppressive regimen concomitant with cyclosporine A
| Overall
|
Patients who completed steroid withdrawal
|
Patients who did not complete steroid withdrawal
|
|||||||
|---|---|---|---|---|---|---|---|---|---|
| Azathioprine (n = 75) | MMF (n = 72) | P | Azathioprine (n = 50) | MMF (n = 47) | P | Azathioprine (n = 25) | MMF (n = 25) | P | |
| Delayed graft function | 17 (22.7) | 16 (22.2) | 0.95 | 12 (24.0) | 9 (19.2) | 0.56 | 5 (20.0) | 7 (28.0) | 0.51 |
| Proteinuria | 19 (25.3) | 19 (26.4) | 0.88 | 14 (28.0) | 11 (23.4) | 0.60 | 5 (20.0) | 8 (32.0) | 0.33 |
| Diabetes | 14 (18.7) | 10 (13.9) | 0.43 | 11 (22.0) | 4 (8.5) | 0.07 | 3 (12.0) | 6 (24.0) | 0.46 |
| Rejection | 43 (57.3) | 30 (41.7) | 0.06 | 27 (54.0) | 17 (36.2) | 0.08 | 16 (64.0) | 13 (52.0) | 0.39 |
| Graft loss | 3 (4.0) | 3 (4.2) | 0.99 | 1 (2.0) | 0 (0) | 0.99 | 2 (8.0) | 3 (12.0) | 0.99 |
| Cardio/cerebro-vasculara | 11 (14.5) | 14 (19.4) | 0.44 | 8 (16.0) | 8 (17.0) | 0.89 | 3 (12.0) | 6 (24.0) | 0.46 |
| Infectionsa | 54 (72.0) | 43 (59.7) | 0.12 | 37 (74.0) | 27 (57.4) | 0.09 | 17 (68.0) | 16 (64.0) | 0.77 |
| cytomegalovirus | 27 (36.0) | 23 (31.9) | 0.60 | 20 (40.0) | 15 (31.9) | 0.41 | 7 (28.0) | 8 (32.0) | 0.76 |
| urinary tract infection | 23 (30.7) | 26 (36.1) | 0.49 | 18 (36.0) | 16 (34.0) | 0.84 | 5 (20.0) | 10 (40.0) | 0.12 |
| other causes | 38 (50.7) | 29 (40.2) | 0.21 | 24 (48.0) | 16 (34.0) | 0.16 | 14 (56.0) | 13 (52.0) | 0.78 |
| Cancersa | 9 (12.0) | 5 (6.9) | 0.30 | 7 (14.0) | 2 (4.3) | 0.16 | 2 (8.0) | 3 (12.0) | 0.99 |
Data are n (%). MMF, mycophenolate mofetil.
a
Some patients have recorded >1 event.