TABLE 2.
Number of Outcomes Prevented with Population-Based and Targeted Prevention Strategies
| Outcomes Prevented over 5 Years among Adults 30+Years of Age with No History of CV Disease | ||||||||
|---|---|---|---|---|---|---|---|---|
| % Adult Population Treated | Total in U.S. Population (in Millions) | Rate per 1,000 Persons Treated | NNTa | |||||
| Treatment Scenario | Events | Mortality | Events | Mortality | Events | Mortality | ||
| Population-based strategy | Low intensity | 100 | 0.75 | 0.14 | 6.4 | 1.2 | 156 | 850 |
| Moderate intensity | 100 | 1.87 | 0.34 | 16.0 | 2.9 | 62 | 340 | |
| LDL-targeted strategy | 25 | 0.79 | 0.15 | 27.1 | 5.2 | 37 | 193 | |
| Risk-targeted strategy | 25 | 1.56 | 0.40 | 53.8 | 13.7 | 19 | 73 | |
NNT = Number needed to treat to prevent one CV event or CV death.