TABLE 5.

Examples of Extreme Discordance between LDL Levels and CV Risk

	A: High LDL, Low CV Risk	B: Low LDL, High CV Risk
Age	45	68
Sex	Female	Male
LDL	175	95
HDL	55	25
Triglycerides	100	200
Systolic blood pressure	120	145
Left ventricular hypertrophy by ECG	No	Yes
Tobacco use	No	Yes
5-year risk of CV event	1.3%	40.6%
5-year risk of CV mortality	< 0.1%	13.2%

Note: Values in boldface indicate risk factors for CV events and mortality.

To illustrate the concept of risk stratification, this table compares the risks of two individuals. Despite having a high LDL, individual A has a 1.3 percent risk of a cardiovascular event in the next five years, and less than 0.1 percent risk of mortality due to such an event. But individual B has a 40.6 percent risk of a cardiovascular event in the next five years and a 13.2 percent risk of mortality from such an event.