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. 2009 Apr 6;27(16):2638–2644. doi: 10.1200/JCO.2008.17.9549

Table 4.

Cardiac Events After Completion of T for Patients Receiving IMN RT

Cardiac Event AC-T (RT only)
AC-T-H (RT only)
AC-TH-H (RT only)
All RT Patients
All RT Patients
IMN RT No IMN RT IMN RT No IMN RT IMN RT No IMN RT IMN RT No IMN RT
Patients, No. 15 468 14 508 15 398 44 1,374 1,418
Confirmed CHF, No. 0 1 1 13 0 7 1 21 22
Cardiac deaths, No. 1 0 0 0 0 0 1 0 1
Cardiac events, No. 1 1 1 13 0 7 2 21 23

NOTE. Three-year cumulative incidence rates were as follows: AC-T: IMN RT, 0%; no IMN RT, 0.2%; AC-T-H: IMN RT, 7.1%; no IMN RT, 2.6%; and AC-TH-H: IMN RT, 0%; no IMN RT, 1.8%.

Abbreviations: T, paclitaxel; IMN, internal mammary nodes; RT, radiotherapy; AC, doxorubicin and cyclophosphamide; H, trastuzumab; CHF, congestive heart failure.