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Percent of APOE Genotypes in Controls and Individuals with AD
| APOE Genotype | Normal Controls (n=304) | All Individuals with AD (n=233) | Individuals with AD and Positive Family History of Dementia 1 (n=85) |
|---|---|---|---|
| e2/e2 | 1.3% | 0% | 0% |
| e2/e3 | 12.5% | 3.4% | 3.5% |
| e2/e4 | 4.9% | 4.3% | 8.2% |
| e3/e3 | 59.9% | 38.2% | 23.5% |
| e3/e4 | 20.7% | 41.2% | 45.9% |
| e4/e4 | 0.7% | 12.9% | 18.8% |
Modified from Jarvik et al66
Most families would be considered to have late-onset familial AD.
