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. 2009 Jun 12;4(6):e5894. doi: 10.1371/journal.pone.0005894

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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The muscle hypertrophic response was evaluated 5 weeks after DNA electrotransfer in mice placed on the regular chow diet. Each group consisted of 8 mice. For A and B, data from muscles from control mice (control), the contra lateral leg of the EPO transfected mice (contralateral), and the EPO transfected leg (EPO) are shown. Means±SEM are depicted. A) Total muscle weight, B) phosporylated Akt determined by Western Blotting, C) expression of muscle fibre protein (Q-PCR) in control and EPO transfected muscles, and D) muscle stamina in % of the control leg. Statistical significance was tested by Student's t-test with Bonferroni corrections for multiple testing. * indicates significance at p<0.05.