Table 2. Early changes in metabolic parameters one week after EPO electrotransfer.
Normal diet | High-fat diet | |||||
Control | EPO | P-value | Control | EPO | P-value | |
Hgb (mmol/l) | 7.6±0.3 | 10.4±0.5 | 0.0002 | 8.4±0.2 | 10.7±0.3 | 6.5E-6 |
Serum EPO (pg/ml) | 52±10 | 1940±400 | 0.0007 | 39±9 | 1664±338 | 0.0003 |
Fasting glucose (mmol/l) | 4.1±0.2 | 3.7±0.3 | 0.22 | 6.2±0.6 | 5.0±0.3 | 0.098 |
Fasting insulin (pg/ml) | 847±170 | 699±233 | 0.62 | 1861±337 | 836±126 | 0.012 |
Glucose sensitivity (AUC) | 1991±51 | 2076±92 | 0.44 | 1459±29 | 1379±42 | 0.14 |
Means±SEM of Hgb, serum EPO, fasting glucose and insulin, and glucose sensitivity one week after EPO electrotransfer (n = 8 in each group). Statistical significance is tested by Student's T-test with Bonferroni correction for multiple testing.