Table 1.
Expression of claudin, occludin, zonula occludens-1, and E-cadherin in adult human and rodenta,b,c endoneurium
| Paranodal area
|
Schmidt-Lanterman incisure
|
Mesaxon
|
Node of Ranvier
|
|
|---|---|---|---|---|
| Proteins | Human/rodenta | Human/rodent | Human/rodent | Human/rodent |
| Claudin-1 | +/+ | +/− | +/+ | −/− |
| Claudin-2 | +/− | +/− | +/− | −/+ |
| Claudin-3 | −/−d | +/− | +/− | −/− |
| Claudin-5 | −/− | +/+ | −/− | −/− |
| Occludin | +e/−b | +e/−b | +/−b | −/−b |
| Zonula occludens-1 | +/+ | +/+ | +/+ | −/− |
| E-cadherin | +/+c | +/+c | +/+c | −/−c |
b
Nagaoka et al. 1999.
d
Claudin-3 was detected in paranodal areas of human fetal nerves at 37 weeks.
e
Occludin labeling in Schmidt-Lanterman incisures and paranodal areas of fetal nerves could not be distinguished from each other.