Figure 1.

Sensitisation of Escherichia coli to CB1954 by the expression of NfsA or NfsB. Log phase cultures of E. coli UT5600 stably lysogenised with bacteriophage λ-vectors expressing NfsA or NfsB, or empty vector as control, were diluted and plated on agar containing 0, 50, 100, 200 or 300 μM CB1954. Colonies were counted after 24 h, and expressed as a percentage (%) of the number obtained from the same liquid culture plated in the absence of a prodrug (mean and range of duplicates).