Table II.
c-statistics for CEP markers
The c-statistic and 95% CI were determined by a logistic regression model fitted with log-transformed CEP adduct concentration and autoantibody titer as independent variables and were validated by bootstrap resampling and 10-fold cross-validation.
| n | Total
|
Bootstrap validation
|
Cross-validation
|
||||
|---|---|---|---|---|---|---|---|
| Estimate | 95% CI | Estimate | 95% CI | Estimate | 95% CI | ||
| Control | 488 | ||||||
| All AMD | 916 | 0.76 | 0.73, 0.79 | 0.76 | 0.73, 0.79 | 0.76 | 0.73, 0.78 |
| AMD category 2 | 177 | 0.76 | 0.72, 0.80 | 0.76 | 0.72, 0.80 | 0.75 | 0.71, 0.79 |
| AMD category 3 | 130 | 0.73 | 0.68, 0.77 | 0.73 | 0.69, 0.78 | 0.72 | 0.68, 0.77 |
| AMD category 4 | 609 | 0.77 | 0.74, 0.80 | 0.77 | 0.74, 0.80 | 0.77 | 0.74, 0.80 |