Table II.
Functional analysis
Proteins identified were uploaded to the Ingenuity Pathways Knowledge Base and subjected to functional analysis. This identifies functions and diseases in which the proteins have previously been found to be altered. Abbreviations are as in Table I. Up-regulated proteins are shown in bold.
| Global function | p value | Proteins |
|---|---|---|
| Nuclei acid metabolism | 0.0003 | DPYSL2, MTAP, NUDT2, VDAC1, IDH1 |
| Neurological disease | 0.0005 | MBP, CNP, DPYSL2, VDAC1, SOD2, IDE, UCHL1, MDH1 |
| Cellular assembly and organization | 0.0006 | CNP, DPYSL2, DSTN, MBP, ANXA5, TST, CPLX1, FIS1, GRB2, CAPNS1, SOD2, UCHL1, DNM1 |
| Cellular function and maintenance | 0.001 | VDAC1, SOD2 |