Table 1.
Clinical Characteristics of the Study Sample
| Intermittent claudication |
Ankle-brachial Index |
||||
|---|---|---|---|---|---|
| Variable Mean (SD) or percent | Yes or Vascular Intervention N=90 | No N=2710 | <0.9 N=111 | 0.9 to 1.0 N=225 | >1.0 to 1.4 N=2464 |
| Age, years | 67 (9) | 61 (9) | 70 (8) | 65 (10) | 60 (9) |
| Women, % | 43 | 54 | 50 | 71 | 52 |
| Current smoking, % | 27 | 13 | 30 | 26 | 12 |
| Pack years among ever smokers, mean | 63 (25) | 43 (23) | 65 (25) | 47 (23) | 41 (22) |
| Diabetes, % | 29 | 12 | 26 | 20 | 11 |
| Body mass index, kg/m2 | 29.7 (6.1) | 28.0 (5.1) | 28.2 (5.5) | 28.5 (6.6) | 28.0 (4.9) |
| Total/HDL cholesterol ratio | 4.5 (1.4) | 4.0 (1.3) | 4.4 (1.5) | 4.0 (1.5) | 4.1 (1.3) |
| Lipid lowering treatment, % | 49 | 19 | 40 | 28 | 19 |
| Hypertension, % | 74 | 44 | 76 | 62 | 42 |
| Hypertension treatment, % | 68 | 32 | 66 | 49 | 31 |
| Aspirin use*, % | 57 | 30 | 49 | 34 | 30 |
| Prevalent cardiovascular disease†, % | 52 | 10 | 33 | 15 | 9 |
| Hormone replacement among women, % | 38 | 30 | 16 | 31 | 31 |
*
aspirin use is defined as 3 or more tablets per week
†
cardiovascular disease did not include intermittent claudication