Table 1.
Clinical and Biological Characteristics of 75 Patients with Idiopathic Hypersomnia and 30 Matched Controls
| Clinical characteristics | Patients | Controls | P |
|---|---|---|---|
| Number | 75 | 30 | |
| Age, y | 34.0 ± 12.5 | 38.6 ± 15.2 | 0.15 |
| BMI, kg/m2 | 24.4 ± 5.0 | 24.4 ± 4.6 | 0.97 |
| Women, % | 64.0 | 50.0 | 0.19 |
| Caucasians, % | 100 | 100 | 1 |
| Hypnagogic hallucinations, % |
24.1 | 8.7 | 0.09 |
| Sleep paralysis, % | 27.6 | 4.3 | 0.01 |
| Non refreshing naps, % | 46.3 | 5.0 | 0.001 |
| Sleep drunkenness, % | 36.5 | 0.0 | < 0.0001 |
| Epworth sleepiness score (0-24) |
15.0 ± 4.2 | 5.4 ± 2.5 | < 0.0001 |
| Pichot fatigue score (0-32) |
26.4 ± 8.3 | 10.6 ± 3.0 | < 0.0001 |
| HAD anxiety (0-21) | 8.7 ± 4.0 | 6.1 ± 3.6 | 0.006 |
| HAD depression (0-21) | 7.1 ± 5.0 | 4.0 ± 3.0 | 0.003 |
| Horne-Ostberg score | 47.8 ± 13.0 | 55.2 ± 8.8 | 0.007 |
| HLA DQB1*0602 positive, % |
24.2 | 19.2 | 0.60 |
HAD: Hospital Anxiety and Depression Rating Scale;
HLA: human leukocyte antigen.
± values = SD.