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Figure 2a. Predicted Hypoxic Selectivity (HCD) and Potency (AUCreq) for BTOs.
Legend for Table 2a: ●compounds predicted inactive; 
, active in vivo; 
, not tested due to structural similarity to actives; 
, not active in vivo. Data from Refs 48 and 49.
Figure 2b. Predicted Hypoxic Selectivity (HCD) and Potency (AUCreq) for TTOs.
Legend for Table 2b: ● TTOs from Table 1; 
, TTOs from Table 2; 
, TTOs from Table 3.
