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. Author manuscript; available in PMC: 2010 May 1.
Published in final edited form as: Dev Biol. 2009 Mar 6;329(1):130–139. doi: 10.1016/j.ydbio.2009.02.036

Figure 6. A proposed model for the regulation of mesoderm formation by ΔNp63, p53, activin and nodal-related proteins.

Figure 6

(A) ΔNp63 α activity predominates in cells that acquire epithelial cell fates and suppresses expression of activin and nodal target genes. (B) In cells that acquire mesodermal fate, activin and nodal-related proteins signal through p53 to transcriptionally up-regulate target genes.