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. Author manuscript; available in PMC: 2009 Jun 3.
Published in final edited form as: Ann Neurol. 2009 May;65(5):520–530. doi: 10.1002/ana.21592

Fig 2.

Fig 2

Delayed PFT-α treatment improved locomotor behavior in stroke rats. (A) Time line indicates that rats were subjected to a 90- min MCAo surgery on day 0. Vehicle or PFT-α was given from day 6 for four consecutive days. Behavioral measurements were carried out in automated activity chambers for 24 hours at 2 (before administration of PFT-α or vehicle), 14 and 21 days after MCAo. No difference was found before PFT-α or vehicle injection on day 2. Rats receiving post-stroke PFT-α treatment show enhanced recovery in motor function demonstrated by significant increases in (B) horizontal activity (total number of beam interruptions in the horizontal sensors), (C) total distance traveled, (D) number of movements, and (E) vertical activity (total number of beam interruptions in the vertical sensors), compared to the control group. (Δ, p<0.05, 2-way ANOVA; * p<0.05, post-hoc Newman-Keuls test).