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. Author manuscript; available in PMC: 2010 Jun 12.
Published in final edited form as: Vaccine. 2009 May 9;27(29):3811–3820. doi: 10.1016/j.vaccine.2009.04.054

Fig. 5.

Fig. 5

Rhesus macaques were vaccinated intramuscularly with 22.5 μg of Fluzone® and increasing amounts of JVRS-100 (2.5, 7.5 22.5 μg) at Day 0 and 14. Viral strain-specific HAI antibody and microneutralization titers were determined, and demonstrated significantly higher antibody titers after vaccination with Fluzone® plus JVRS-100 compared to Fluzone® alone. (A) influenza A H1N1 (A/New Caledonia/20/99)-specific HAI-titers ***P<0.0005. (B) influenza A H3N2 (A/Wisconsin/67/2005)-specific HAI-titers *P<0.05. (C) influenza B (B/Malaysia/2506/2004)-specific HAI titers *P<0.05). (D) influenza A H1N1-specific microneutralization titers ***P<0.0005. (E) influenza A H3N2-specific microneutalization titer *P<0.05. (F) influenza B-specific microneutalization titers **P<0.005). P values were calculated using a two-way ANOVA test.