Table 2.
Comparative HCLPE studies
| Study | Name of the HCLPE/CPE | Number of THAs (study/control = total) | Followup (years)* | Annual wear HCLPE/CPE (mm/year)† | p Value | Periprosthetic osteolysis | p Value |
|---|---|---|---|---|---|---|---|
| Glyn-Jones et al. [18] (2008) | Longevity®/CPE (Zimmer, Inc, Warsaw, IN) | 26/25 = 51 | 2 (not given) | 0.06 ± 0.06/0.10 ± 0.07 | 0.04 | Not studied | |
| Martell et al. [33] (2003) | Crossfire™/N2/Vac™ (Stryker Howmedica Osteonics, Allendale, NJ) | 24/22 = 46 | 2.3 (1.8–3.2) | 0.12 ± 0.05/0.20 ± 0.1 | 0.001 | Not studied | |
| Geerdink et al. [17] (2006) | Duration™/CPE (Stryker) | 45/54 = 99 | 4.7 (3.3–5.9)/4.7 (3.1–5.5) | 0.083 ± 0.056/0.12 ± 0.082 | 0.04 | Acetabular 1/4 hips | Not given |
| Femoral 1/5 hips | |||||||
| Digas et al. [9] (2007) | Durasul®/Sulene™ (cemented) (Zimmer) | 28/27 = 55 | 5 (not given) | 0.15 (−0.1–0.86)/0.36 (−0.27–1.12) | < 0.001 | Not studied | |
| Longevity®/CPE (hybrid) (Zimmer | 19/19 = 38 | 5 (not given) | 0.08 (−0.02–0.24)/0.34 (0.09–1.41) | < 0.001 | Not studied | ||
| Dorr et al. [12] (2005) | Durasul®/Sulene™ (Zimmer) | 23/17 = 40 | 5 (not given) | 0.029 ± 0.02/0.065 ± 0.026 | < 0.005 | Not studied | |
| Engh et al. [14] (2006) | Marathon™/Enduron™ (DePuy Orthopaedics, Inc, Warsaw, IN) | 86/83 = 169 | 5.5 (4.1–7.0) | 0.01 ± 0.07/0.20 ± 0.13 | < 0.001 | 24%/57.8% incidence of any osteolysis | < 0.001 |
| Röhrl et al. [43] (2007) | Crossfire™/Exeter™ (Stryker) | 9/12 = 21 | 5/6 (not given) | 0.006/0.072 | Not given | Not studied | |
| Bitsch et al. [1] (2008) | Marathon™/Enduron™ (DePuy) | 32/24 = 56 | 5.8 (5–7.7) | 0.031 ± 0.047/0.104 ± 0.094 | 0.003 | 0/8 hips | < 0.001 |
| Current study | Longevity®/CPE (Zimmer) | 41/41 = 82 | 5.3 (4–8) | 0.002 ± 0.084/0.12 ± 0.071 | < 0.001 | 2/8 hips | 0.9 |
*Values are expressed as average, with range in parentheses; †values are expressed as mean ± standard deviation or as average, with range in parentheses; HCLPE = highly cross-linked polyethylene; CPE = conventional (noncross-linked) polyethylene.