Table 1.

Demographics, comorbidities, treatment, and outcome data of the 18 patients followed up

Patient	Gender	Age	Comorbidities	Time of presentation(after ORIF)	HW status	Initial surgery	Intraoperative culture results	Antibiotics	Recurrence of infection	Comments	Amputation
1	F	38	Low albumin, hypothyroidism	1 week	Intact	ID, HW retained	S. epidermidis	Daptomycin	Yes (7 weeks after ID)	Ulceration with exposed bone at medial distal tibia	Yes
2	M	31	None	2 weeks	Intact	ID, HW retained	OSSA	Cefazolin	Yes (8 weeks after ID)	Repeat ID, HW removed	No
3	M	53	Low albumin, smoking, alcohol	2 weeks	Intact	ID, HW retained	ORSA	Vancomycin, then PO Bactrim	Yes (7 weeks after ID)	Repeat ID, HW removed	No
4	M	54	Low albumin, smoking, alcohol	7 weeks	Loose	ID, HW removed	OSSA	Oxacillin then PO cefazolin	Yes (14 weeks after ID)	Repeat ID	No
5	F	58	DM, retinopathy, peripheral neuropathy, low albumin	7 weeks	Loose	ID, HW removed	OSSA	Oxacillin plus rifampin	Yes (3 weeks after ID)		Yes
6	M	21	Low albumin, smoking	3 weeks	Intact	ID, HW retained	S. epidermidis, Propionibacterium	Vancomycin	No	Repeat ID, HW removed	No
7	M	37	HIV, hepatitis C, IVDA, smoking	5 weeks	Intact but fibula malreduced	ID, HW removed	Serratia, Acinetobacter	Vancomycin, levofloxacin, amikacin	No		No
8	M	52	IVDA, smoking, alcohol	9 weeks	Loose	ID, HW removed	OSSA	Oxacillin	No		No
9	M	30	None	11 weeks	Intact	ID, HW removed	OSSA	Cefazolin plus rifampin	No		No
10	M	40	Smoking	13 weeks	Intact	ID, HW removed	S. epidermidis	Vancomycin	No		No
11	M	44	DM, IVDA, smoking, low albumin	14 weeks	Intact	ID, HW removed	OSSA	Cefazolin	No		No
12	M	59	DM, alcohol, low albumin	15 weeks	Intact	ID, HW removed	Enterobacter cloacae, S. epidermidis	Vancomycin, levofloxacin	No		No
13	M	49	None	13 months	Intact	ID, HW removed	ORSA	Vancomycin	No		No
14	M	33	Low albumin	44 weeks	Intact	ID, HW removed	ORSA	Vancomycin	No		No
15	M	36	Smoking	12 months	Loose	ID, HW removed	ORSA	Vancomycin	No		No
16	F	36	Smoking	21 months	Intact	ID, HW removed	OSSA, S. epidermidis	Vancomycin	No		No
17	M	30	Low albumin	4.5 years	Loose	ID, HW removed	ORSA	Vancomycin plus rifampin	No		No
18	F	47	DM, IVDA, hepatitis B, hepatitis C, cirrhosis, low albumin, smoking	23 months	Loose	Amputation	Not available (S. epidermidis in preoperative cultures)	Ertapenem plus levofloxacin (before amputation)	No	Ulcerations of lateral and medial side of ankle, joint destruction	Yes

HW = hardware; ORIF = open reduction internal fixation; HIV = human immunodeficiency virus; IVDA = intravenous drug abuse; DM = diabetes mellitus; OSSA = oxacillin sensitive Staphylococcus aureus; ORSA = oxacillin resistant Staphylococcus aureus.