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In vitro release of ibuprofen from anhydride conjugates of ibuprofen and polymers as measured by high-performance liquid chromatography. The polymers were: polyacrylic acid 2,000 Da (diamond), polyacrylic acid 5,000 Da (open circle), cross-linked polyacrylic acid (square), Eudragit® L-100 (triangle), Eudragit® S-100 (ex), polyacrylic acid 2,000 Da at pH 2 (filled circle). Experiments were performed in phosphate buffer (pH 7.4) at 37°C
