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. 2009 May 8;10(2):540–546. doi: 10.1208/s12249-009-9238-x

Table II.

Effect of pH on Labeling Efficiency of Timolol Maleate

pH Percent of labeling efficiency Percent of free Tc Percent of colloids
5 87 ± 0.2 12.3 ± 0.3 0.7 ± 0.3
5.5 90 ± 0.3 8 ± 0.2 2 ± 0.13
6.0 97.5 ± 0.1 2.0 ± 0.5 0.5 ± 0.12
6.5 98.2 ± 0.3 0.8 ± 0.12 0.2 ± 0.03
7.0 94 ± 0.2 5 ± 0.1 1 ± 0.3
7.5 90 ± 0.1 8 ± 0.3 2 ± 0.2

All values are expressed as mean ± SD (n = 5)