Figure 4.

Interaction of nu61 and SCC61 cells partially protects SCC61 from cell death and is associated with differential secretion of IL6, sIL6R and IL8. Nu61 cells were labeled with CFDA-SE (upper quadrants in panel A) to distinguish them from SCC61 (lower quadrants of panel A). Cells were co-cultured and treated as described in Methods. Although nu61 do not completely rescue SCC61 from cytotoxic treatments (panel A), SCC61 cells in co-culture compared with SCC61 cells in monoculture (panel B) are more resistant to cell death. Shown on panel B are mean values of three independent experiments +/− SE.