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Voltage-dependent gating of gap junction channels in A7r5 cells (A), Rat-1 cells (B), and N2A-Cx40 cells (C). Normalized junctional conductance [steady state relative to instantaneous (Gss/Ginst)] is plotted as a function of transjunctional voltage for 10 A7r5, 7 Rat-1, and 6 N2A-Cx40 cell pairs. Note the uniformity of responses to voltage in the Rat-1 and N2A cells compared with the diversity observed in the A7r5 cells.
