TABLE 3.
NAAT performance statistics for Neisseria gonorrhoeae
| Test | % (no. of positive samples confirmed/total no. of positive samples) (CIa)
|
|||||||
|---|---|---|---|---|---|---|---|---|
| Sensitivity
|
Specificity
|
PPV
|
NPV
|
|||||
| First 500 | Total 1,000 | First 500 | Total 1,000 | First 500 | Total 1,000 | First 500 | Total 1,000 | |
| ProbeTec SDA | 80 (4/5) (28.4-99.5*) | 80 (12/15) (51.9-95.7*) | 100 (495/495) (99.3-100**) | 100 (985/985) (99.6-100*) | 100 (4/4) (39.8-100**) | 100 (12/12) (73.5-100**) | 99.8 (495/496) (98.9-99.9*) | 99.7 (985/988) (99.1-99.9*) |
| Aptima Combo2 | 100 (5/5) (47.8-100**) | 100 (15/15) (78.2-100**) | 100 (495/495) (99.3-100**) | 100 (985/985) (99.6-100**) | 100 (5/5) (47.8-100**) | 100 (15/15) (78.2-100**) | 100 (495/495) (99.3-100**) | 100 (985/985) (99.6-100**) |
| Roche Amplicor PCR | 100 (5/5) (47.8-100**) | NAb | 98.8 (489/495) (97.4-99.6*) | NA | 45.5 (5/11) (16.7-76.6*) | NA | 100 (489/489) (99.2-100*) | NA |
a
*, 95% confidence interval (CI); **, 97.5% CI.
b
NA, not applicable.