TABLE 1.
Detection of N. gonorrhoeae and C. trachomatis by NAATs with self-collected glans swab specimensa
| Test | Specimen | Sensitivity (%)
|
|||
|---|---|---|---|---|---|
|
N. gonorrhoeae
|
C. trachomatis
|
||||
| Method 1 | Method 2 | Method 1 | Method 2 | ||
| SDA | Glans swab | 92.5 (74/80)b | 75.0 (21/28) | 56.3 (18/32)c | 60.7 (17/28) |
| AC2 | Glans swab | 96.3 (77/80) | 82.1 (23/28) | 59.4 (19/32)d | 67.9 (19/28) |
| AC2 | FCU | 97.5 (78/80) | 96.4 (27/28) | 93.8 (30/32) | 82.1 (23/28) |
True-positive results are defined as a positive result by AC2 with FCU, positive results for glans swab specimens by both NAATs, or a positive result by a single NAAT with glans swab specimens confirmed by an alternate amplification method. The specificities of all assays were ≥99.7%. For specimen collection by methods 1 and 2, the prevalence rates of N. gonorrhoeae were 16.3 (80/492) and 7.2 (28/390), respectively, and those of C. trachomatis were 6.5 (32/492) and 7.2 (28/390), respectively.
The values in parentheses are the number of MSM positive/total number of MSM tested.
P = 0.0005 by comparison with the results of AC2 with FCU.
P = 0.001 by comparison with the results of AC2 with FCU.