TABLE 4.
Detection of N. gonorrhoeae and C. trachomatis by NAATs with rectal swab specimensa
| Rectal swab specimen collector | Test |
N. gonorrhoeae (n = 882)
|
C. trachomatis (n = 907)
|
||
|---|---|---|---|---|---|
| Sensitivitya (%) | Specificity (%) | Sensitivity (%) | Specificity (%) | ||
| Self | SDA | 77.1 (64/83)b,c | 99.3 (793/799) | 40.9 (27/66)c | 100 (841/841) |
| Clinician | SDA | 67.5 (56/83)c | 100 (799/799) | 43.9 (29/66)c | 99.9 (840/841) |
| Self | AC2 | 84.3 (70/83)c | 100 (799/799) | 81.8 (54/66)c | 100 (841/841) |
| Clinician | AC2 | 78.3 (65/83)c | 99.8 (797/799) | 71.2 (47/66)c | 99.6 (838/841) |
| Clinician | Culture | 34.9 (29/83) | 100 (799/799) | 18.2 (12/66) | 100 (837/837) |
a
True-positive results were defined as positivity by culture, positive results by two or more NAATs, or a positive result by a single NAAT confirmed by an alternate amplification method. The overall prevalence rates of C. trachomatis were 9.8% (43/438) for asymptomatic MSM and 4.9% (23/469) for symptomatic MSM. The overall prevalence rates of N. gonorrhoeae were 8.0% (33/413) for asymptomatic MSM and 10.7% (50/469) for symptomatic MSM.
b
The values in parentheses are the number of MSM positive/total number of MSM tested.
c
All P values were <0.005 by comparison with the results of culture.