TABLE 2.
Activities of seven antifungal agents against 49 A. fumigatus strains collected by the SENTRY Program in 2006 to 2007
| Agent | MIC50/MIC90 (μg/ml) | MIC range (μg/ml) | % of isolates inhibited by ≤1 μg/mla |
|---|---|---|---|
| Anidulafungin | 0.004/0.008 | ≤0.001-0.008 | 100.0 |
| Caspofungin | 0.12/0.12 | ≤0.008-0.12 | 100.0 |
| Amphotericin B | 2/2 | ≤0.12-2 | 71.4 |
| 5-FC | >64/>64 | 8->64 | 0.0 |
| Itraconazole | 1/1 | 0.25-1 | 100.0 |
| Posaconazole | 0.5/0.5 | ≤0.06-0.5 | 100.0 |
| Voriconazole | 0.5/1 | 0.25-1 | 100.0 |
a
Breakpoint criteria have not been established by the CLSI (2008). For comparison, the percent inhibited by ≤1 μg/ml was used (3).