TABLE 3.
Sensitivities and cross-reactions of sera from patients with other helminthic infections in rTES ELISAs using IgG subclasses, IgE, and IgM
| ELISA and antigen | No. of positive samples/total no. of samples (%)
|
||||||
|---|---|---|---|---|---|---|---|
| Sensitivity to toxocariasis | Cross-reactivity with serum from source
|
Total cross-reactivity | |||||
| Patients with:
|
Healthy individuals | ||||||
| STH infection | B. malayi microfilaremia | Amoebiasis | Toxoplasmosis | ||||
| IgG1 | |||||||
| rTES-26 | 8/20 (40) | 8/15 | 3/10 | 4/10 | 6/10 | 1/20 | 22/65 (33.8) |
| rTES-30USM | 8/20 (40) | 8/15 | 3/10 | 5/10 | 6/10 | 1/20 | 23/65 (35.4) |
| rTES-120 | 10/20 (50) | 8/15 | 3/10 | 5/10 | 6/10 | 2/20 | 24/65 (36.9) |
| IgG2 | |||||||
| rTES-26 | 11/20 (55) | 5/15 | 2/10 | 3/10 | 3/10 | 3/20 | 16/65 (24.6) |
| rTES-30USM | 11/20 (55) | 8/15 | 2/10 | 5/10 | 3/10 | 3/20 | 21/65 (32.3) |
| rTES-120 | 15/20 (75) | 8/15 | 2/10 | 5/10 | 4/10 | 3/20 | 22/65 (33.8) |
| IgG3 | |||||||
| rTES-26 | 8/20 (40) | 4/15 | 2/10 | 2/10 | 3/10 | 3/20 | 14/65 (21.5) |
| rTES-30USM | 8/20 (40) | 5/15 | 2/10 | 4/10 | 5/10 | 2/20 | 18/65 (27.7) |
| rTES-120 | 9/20 (45) | 5/15 | 2/10 | 4/10 | 4/10 | 3/20 | 18/65 (27.7) |
| IgE | |||||||
| rTES-26 | 10/20 (50) | 4/15 | 3/10 | 3/10 | 2/10 | 3/20 | 15/65 (23) |
| rTES-30USM | 11/20 (55) | 5/15 | 3/10 | 3/10 | 3/10 | 3/20 | 17/65 (26.2) |
| rTES-120 | 11/20 (55) | 5/15 | 3/10 | 3/10 | 3/10 | 3/20 | 17/65 (26.2) |
| IgM | |||||||
| rTES-26 | 1/12 (8.33) | 2/11 | 0/5 | 0/5 | 1/4 | 2/5 | 5/30 (16.7) |
| rTES-30USM | 1/12 (8.33) | 2/11 | 1/5 | 0/5 | 1/4 | 2/5 | 6/30 (20) |
| rTES-120 | 4/12 (33.3) | 3/11 | 3/5 | 1/5 | 0/4 | 3/5 | 10/30 (33.3) |