TABLE 2.
Origins and MLVA results for the armadillo-derived M. leprae isolates used in this studya
| Taxonb | Isolate or animal code (passage no.) | Other isolate(s) (passage no.) | Yr of origin | Country of origin of donor | Region | VNTR pattern at locusc:
|
|||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| (AT)17 | (TA)18 | (AC)8a | (AT)15 | (TA)10 | (AC)8b | (AC)9 | (TTC)21 | (GTA)9 | (GGT)5 | 6-7 | 12-5 | 18-8 | 21-3 | 23-3 | 27-5 | ||||||
| 1 | TN | 1980 | India | IN | 17 | 18 | 8 | 15 | 10 | 8 | 9 | 21 | 9 | 5 | 7 | 5 | 8 | 3 | 3 | 5 | |
| 2 | CD236 (0) | 1977 | India | IN | 16 | N | 8 | 15 | 10 | 8 | 9 | 21 | 9 | 5 | 7 | 5 | 8 | 3 | 3 | 5 | |
| 3 | 3045/334 (2) | 336 (2) | 1987 | India | IN | N | 11 | 8 | 13 | 8 | 7 | 10 | 15 | 10 | 5 | 5 | 4 | 7 | 1 | 2 | 5 |
| 4 | 3044/329 (2) | 333 (2), 325 (2), 264 (1), 267 (1) | 1988 | India | IN | N | 9 | 9 | 17 | 10 | 7 | 8 | 15 | 11 | 4 | 7 | 4 | 7 | 2 | 2 | 5 |
| 5 | I480 (1) | I478 (1) | 1985 | Philippines | OR | 16 | 19 | 8 | 15 | 10 | 8 | 9 | 21 | 9 | 5 | 7 | 5 | 8 | 3 | 3 | 5 |
| 6 | A606 (2) | NA | Philippines | OR | 11 | 17 | 11 | 12 | 13 | 6 | 7 | 13 | 9 | 5 | 5 | 4 | 8 | 3 | 2 | 5 | |
| 7 | W88 (1) | 1976 | Philippines | OR | 12 | 18 | 11 | 16 | 11 | 8 | 8 | 28 | 15 | 5 | 7 | 4 | 8 | 3 | 2 | 5 | |
| 8 | W112 (2) | NA | Philippines | OR | 11 | 18 | 9 | 16 | 11 | 8 | 8 | N | 14 | 5 | 7 | 4 | 8 | 3 | 2 | 5 | |
| 9 | I226 (1) | A308 (2) | NA | Thailand | OR | 11 | 16 | 10 | 12 | 13 | 6 | 7 | 13 | 9 | 5 | 5 | 4 | 8 | 3 | 2 | 5 |
| 10 | A344 (3) | 1980 | Thailand | OR | 11 | 21 | 10 | 14 | 10 | 8 | 7 | 14 | 9 | 4 | 8 | 4 | 8 | 2 | 2 | 5 | |
| 11 | 3039/321 (2) | 3017 (1) | 1987 | Ethiopia | AFR | 13 | 13 | 8 | 20 | 11 | 7 | 10 | 29 | 8 | 5 | 6 | 4 | 8 | 3 | 3 | 5 |
| 12 | I487 (1) | NA | Guyana | SAM | 12 | 17 | 10 | 12 | 13 | 6 | 7 | 13 | 9 | 5 | 5 | 4 | 8 | 3 | 2 | 5 | |
| 13 | 2936/41 (0) | 1987 | Malawi | AFR | 12 | 16 | 8 | 13 | N | 8 | 7 | 13 | 10 | 5 | 8 | 3 | 7 | 2 | 2 | 5 | |
| 14 | 3035/299 (2) | NA | Malawi | AFR | 12 | 16 | 8, 9 | 12, 13 | 8, 9 | 7, 8 | 7, 8 | 13, 16 | 8, 10 | 4, 5 | 6, 8 | 3, 4 | 6, 7 | 2 | 2 | 5 | |
| 15 | NHDP98 | 1990 | United States | NAM | 11 | 12 | 8 | 14 | 11 | 7 | 8 | 10 | 9 | 4 | 7 | 5 | 8 | 2 | 2 | 4 | |
| 16 | NHDP63 | NA | United States | NAM | 13 | 16 | 10 | 16 | 13 | 7 | 8 | 10 | 10 | 4 | 7 | 5 | 8 | 2 | 2 | 4 | |
| 17 | BR4923 | 1996 | Brazil | SAM | 15 | 18 | 7 | 20 | 8 | 7 | 8 | 12 | 12 | 4 | 6 | 4 | 3 | 2 | 2 | 5 | |
| 18 | Thai-53 | NA | Thailand | OR | 10 | 13 | 11 | 17 | 11 | 7 | 9 | 15 | 9 | 5 | 6 | 5 | 8 | 3 | 2 | 5 | |
| 19 | NHDP10 | 1996 | United States | NAM | 13 | 16 | 10 | 17 | 12 | 7 | 8 | 11 | 10 | 4 | 7 | 5 | 8 | 2 | 2 | 4 | |
| 20 | N1192 | NA | NA | NAM | 10 | 13 | 11 | 17 | 11 | 7 | 9 | 15 | 9 | 5 | 6 | 5 | 8 | 3 | 2 | 5 | |
| 21 | N1200 | NA | NA | NAM | 13 | 16 | 10 | 16 | 14 | 7 | 8 | 10 | 10 | 4 | 7 | 5 | 8 | 2 | 2 | 4 | |
| 22 | NHDP55 | 1996 | United States | NAM | 13 | 20 | 10 | 17 | 13 | 7 | 8 | 12 | 10 | 4 | 7 | 5 | 8 | 2 | 2 | 4 | |
a
N, not tested, PCR negative, or sequence negative; NA, not available; AFR, Africa; IN, India; NAM, North America; OR, Orient; SAM, South America.
b
Based on the reference sequenced strain (4) 2-14, obtained from Mill Hill and FIT, and 15-22 Armadillo-derived human leprosy specimens obtained from NHDP (25).
c
VNTR pattern indicates the number(s) of copies found at the specified VNTR locus.