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Hematoxylin and eosin and immunohistochemical staining of lung tissue from DOX-treated mice. Panels (A) and (B) are ×10 and ×40 magnifications, respectively, of hematoxylin and eosin-stained slides showing relatively normal-appearing tissue with evidence of some hyperplasia. Panels (C) and (D) are immunohistochemical staining of lung tissue slides with antibodies to COX-2 and NF-κβ (Ser276) showing little staining for either protein in the tissues; magnification for IHC ×40.
