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The effects of NT-3 overexpression on ON-OFF RGC dendritic structure persist at P28. (A) Whereas NT-3 OE did not change the dendritic field size of ON RGCs double-labeled with SMI-32, it decreased the dendritic field size of ON-OFF RGCs double-labeled with SMI-32. (B–C) The branch number of SMI-32 positive ON-OFF RGCs increased (B) and their mean dendritic length decreased (C) in NT-3 OE mice at P28.
