Figure 7.

Decreased social interaction in the home cage. (A) An index of activity level. (B) Number of particles in the home cage. Social interaction is expressed as the number of particles in the image of the cage found by automatic detection. When the animals are separated, the particle number is 2. When they are together, the number is 1. Each dot indicates the average particles per hour. During the light cycle (7:00 to 19:00), WT mice stayed in contact with their familiar cage mate, whereas the KO mice tended to stay separated from each other.