Figure 6.

β-catenin positively regulates cell motility in the scratch assay, while transforming growth factor β has little effect. A. The means and 95% confidence intervals of the average distance between cells on either side of the scratch (mm). Statistically significant differences (p < 0.05) compared to the controls are indicated with an asterisk above the bar. B through E. Representative photomicrographs of the gap in the cell cultures. B is from wild type cells, C from cells expressing null β-catenin alleles, D from cells treated with transforming growth factor β, and E is from cells expressing stabilized β-catenin alleles. F. The means and 95% confidence intervals of the number of cells passing through the membrane in the Boyden chamber. Statistically significant differences (p < 0.05) compared to the controls are indicated with an asterisk above the bar.