Table 1.
Baseline characteristics for patients with ST-elevation myocardial infarction, according to hospital type
| Hospital type; no. (%) of patients* |
||||
|---|---|---|---|---|
| All patients | Tertiary referral hospitals† | County hospitals† | ||
| Characteristic | n = 9186 | n = 6214 | n = 2918 | p value‡ |
| Age, yr, mean (standard deviation) | 63.8 (11.8) | 61.9 (12.8) | 63.3 (12.3) | < 0.001 |
| Sex, male | 6293 (68.5) | 4377 (70.4) | 1875 (64.3) | < 0.001 |
| Medical history | ||||
| Hypertension | 4986 (54.3) | 3556 (57.2) | 1391 (47.7) | < 0.001 |
| Diabetes mellitus | 1974 (21.5) | 1357 (21.8) | 598 (20.5) | 0.14 |
| Lipid disorders | 3545 (38.6) | 2597 (41.8) | 920 (31.5) | < 0.001 |
| Current smoker | 4653 (50.7) | 3377 (54.3) | 1252 (42.9) | < 0.001 |
| Prior myocardial infarction | 935 (10.2) | 649 (10.4) | 282 (9.7) | 0.24 |
| Characteristics of the qualifying event | ||||
| Anterior acute myocardial infarction | 4637 (50.5) | 3173 (51.1) | 1444 (49.5) | 0.16 |
| Killip class ≥ 2 | 3043 (33.1) | 2056 (33.1) | 968 (33.2) | 0.93 |
| Time from symptom onset to admission, h§ | n = 7863 | n = 5852 | n =1960 | |
| ≤2 | 2433 (30.9) | 1845 (31.5) | 571 (29.1) | 0.040 |
| > 2–6 | 2957 (37.6) | 2245 (38.4) | 694 (35.4) | 0.010 |
| > 6–12 | 1047 (13.3) | 692 (11.8) | 344 (17.6) | < 0.001 |
| > 12 | 1426 (18.1) | 1070 (18.3) | 351 (17.9) | 0.71 |
| Time from symptom onset to thrombolysis, h§ | ||||
| ≤2 | 1870 (23.8) | 1420 (24.3) | 434 (22.1) | 0.010 |
| > 2–6 | 2059 (26.2) | 1610 (27.5) | 433 (22.1) | < 0.001 |
| > 6–12 | 309 (3.9) | 250 (4.3) | 50 (2.6) | < 0.001 |
| > 12 | 73 (0.9) | 63 (1.1) | 9 (0.5) | < 0.001 |
| In-hospital medication | n = 9186 | n = 6214 | n = 2918 | |
| Thrombolytic therapy | 4556 (49.6) | 3393 (54.6) | 1110 (38.0) | < 0.001 |
| Anticoagulants | 8692 (94.6) | 5937 (95.5) | 2706 (92.7) | < 0.001 |
| Antiplatelet drugs | 8296 (90.3) | 5859 (94.3) | 2388 (81.8) | < 0.001 |
| Acetylsalicylic acid | 5811 (63.3) | 3942 (63.4) | 1829 (62.7) | 0.94 |
| Clopidogrel | 157 (1.7) | 123 (2.0) | 34 (1.2) | 0.007 |
| Acetylsalicylic acid and clopidogrel | 2162 (23.5) | 1635 (26.3) | 518 (17.8) | < 0.001 |
| Other | 166 (1.8) | 157 (2.5) | 7 (0.2) | < 0.001 |
| Primary percutaneous intervention | 179 (1.9) | 179 (2.9) | 0 | < 0.001 |
| In-hospital mortality | 1170 (12.7) | 721 (11.6) | 446 (15.3) | < 0.001 |
Unless otherwise indicated.
For 54 patients, data about type of hospital (tertiary referral or county) were missing.
For comparison between patients admitted to tertiary referral hospitals and those admitted to county hospitals.
Data on the time to treatment were available for 7863 (85.6%) of all study patients and for 7812 (85.5%) of those for whom type of hospital (tertiary referral or county) was known; of the latter group, data on time to treatment were available for 5852 of those treated at tertiary referral hospitals and 1960 of those treated at county hospitals. Among patients who received thrombolytic therapy, time from symptom onset to thrombolysis was available for 4311 patients (3343 of those treated at tertiary referral hospitals, 926 of those treated at county hospitals and 42 of those for whom type of hospital was unknown).