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Percent Bioavailable for Oral Gabapentin Using LAT2 and OCTN1 Distributions
| Dose (mg) | Dave LAT2 F% (R 2, RMSE) | Meier OCTN1 F% (R2, RMSE) | F% without active transport |
|---|---|---|---|
| 400 | 54.8 (0.89, 0.31) | 70.5 (0.25, 0.77) | 5.9 |
| 800 | 46.5 (0.81, 0.62) | 57.0 (0.36, 1.1) | 5.9 |
| 1,200 | 40.7 (0.90, 0.49) | 48.0 (0.31, 1.2) | 5.9 |
| 1,600 | 36.4 (0.83, 0.83) | 41.8 (0.29, 1.5) | 5.9 |
| Ave. R 2 | 0.86 | 0.24 | 5.9 |
