Fig. 4.

Time-activity curves of ¹¹C-SA4503-derived radioactivity in tumour, brain and blood pool. Solid line: animals scanned at baseline (treated with arachid oil only, control group, n = 4); dotted line: other animals scanned after repeated injections of progesterone in arachid oil (progesterone-treated group, n = 4). The PET data were normalized to a body weight of 330 g and an injected radioactivity dose of 20 MBq, as described previously [24]. The effect of progesterone addition on tumour uptake (but not brain or blood pool uptake) was statistically significant