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. Author manuscript; available in PMC: 2009 Jun 5.
Published in final edited form as: Exp Eye Res. 2006 May 23;83(4):709–720. doi: 10.1016/j.exer.2006.03.015

Figure 1.

Figure 1

An approach to biomechanical modeling of surgery and disease in the cornea. Disease is simulated by alteration of the substructural components or their material properties. Surgery is simulated by imposing an ablation profile or incisions. The model is optimized retrospectively by comparing model simulations to analogous experiments in tissue or clinical models. A model optimized with clinical data can then be used prospectively to design and evaluate patient-specific treatment algorithms.