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. 2008 Sep;9(6):409–419. doi: 10.2174/138920208785699571

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©2008 Bentham Science Publishers Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.5/), which permits unrestrictive use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. (3). Survival pathways involved in regulation of Bcl-2 proteins. — Four survival pathways (MAPK, PKB-Akt, IKK, JAK/Stat) are indicated which are linked to a number of transcription factors. Some transcription factors are listed here (NF-κB, Ets1/2, CREB/ATF family, MITF and FoxO, p53, STAT), which control the expression of Bcl-2 proteins.