Table 4.
Population (N) | rs642961, allele A |
||||
---|---|---|---|---|---|
Freq | OR | 95% CI | P-value | PAR % | |
Norway | |||||
CL/P and CPO (406) | 0.27 | 1.29 | 1.05–1.57 | 0.01 | 6% |
CL/P (298) | 0.30 | 1.48 | 1.19–1.83 | 0.0005 | 10% |
CLP (184) | 0.26 | 1.22 | 0.93–1.61 | 0.2 | 5% |
CLO (114) | 0.36 | 1.94 | 1.44–2.62 | 0.00002 | 17% |
CPO (108) | 0.19 | 0.82 | 0.55–1.22 | 0.3 | 0% |
Controls (750) | 0.22 | ||||
Denmark | |||||
CL/P and CPO (107) | 0.27 | 1.28 | 0.91–1.79 | 0.2 | 6% |
CL/P (70) | 0.32 | 1.67 | 1.13–2.45 | 0.009 | 13% |
CLP (37) | 0.27 | 1.30 | 0.76–2.23 | 0.3 | 6% |
CLO (33) | 0.38 | 2.15 | 1.28–3.61 | 0.003 | 20% |
CPO (37) | 0.16 | 0.68 | 0.36–1.29 | 0.2 | 0% |
Controls (495) | 0.22 | ||||
Combined | |||||
CL/P and CPO (513) | 0.27 | 1.28 | 1.08–1.52 | 0.004 | 6% |
CL/P (368) | 0.30 | 1.51 | 1.26–1.82 | 0.00002 | 10% |
CLP (221) | 0.26 | 1.23 | 0.97–1.57 | 0.08 | 5% |
CLO (147) | 0.36 | 1.99 | 1.54–2.57 | 0.0000003 | 18% |
CPO (145) | 0.18 | 0.79 | 0.57–1.09 | 0.13 | 0% |
Controls (1245) | 0.22 |
CL/P, Cleft Lip with or without cleft Palate; CLP, Cleft Lip with cleft Palate; CLO, Cleft Lip Only; CPO, Cleft Palate Only; OR, Odds Ratio; CI, Confidence Interval; PAR, Population Attributable Risk.