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Histological section of the mechanical valve sewing cuff (SC), atrial endocardium (At) and native mitral (M) leaflet tissue. A significant degree of pannus (P) deposition is seen covering the SC region, and extending into the surrounding atrial and native mitral leaflet tissue. Thrombus (arrow) is also seen close to the mitral leaflet region (original magnification ×1.6; Movat pentachrome stain)
