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. Author manuscript; available in PMC: 2010 May 1.
Published in final edited form as: Fertil Steril. 2008 Apr 25;91(5):1848–1852. doi: 10.1016/j.fertnstert.2008.02.101

Table 2.

Rate of change per standard deviation (SD) in insulin resistance in PCOS, as measured by HOMA-IR, in order of importance

Variable Standard rate of change per SD % change per SD
BMI 0.122 +33%
WHR 0.104 +27%
Age −0.046 −10%
log DHEAS −0.042 −9%
log FT 0.038 +9%
log SHBG −0.035 −8%
log HP −0.024 −5%

HOMA-IR is the homeostasis model assessment to estimate insulin resistance, BMI is body mass index, WHR is waist to hip ratio, FT is free testosterone, SHBG is sex hormone-binding globulin, and HP is 17-hydroxyprogesterone. For example, with a BMI increase of one standard deviation, the insulin resistance, as measured by HOMA-IR, increases by 33%.