Table 2.
Parameters of spin–spin distance distributions obtained by orientation averaging DEER experiments and Tikhonov regularization (mean, maximum and width at half height) for undamaged [4;19] duplex and selected lesions
| DNA duplex | r[4;19]Mean | r[4;19]Max | w |
|---|---|---|---|
| Undamaged duplex | 5.22 ± 0.04 | 5.21 ± 0.04 | 0.33 ± 0.02 |
| 8-OxoG (7′) | 5.26 ± 0.04 | 5.23 ± 0.04 | 0.35 ± 0.03 |
| 8-OxoG (14′) | 5.25 ± 0.04 | 5.22 ± 0.04 | 0.33 ± 0.03 |
| Abasic site (THF) | 4.95 ± 0.05 | 4.97 ± 0.03 | 0.42 ± 0.03 |
| Ethyl | 5.04 ± 0.05 | 5.02 ± 0.03 | 0.39 ± 0.05 |
| Propyl | 4.89 ± 0.05 | 5.02 ± 0.03 | 0.44 ± 0.05 |
Error values were obtained with a procedure described in the text (‘Results’ section).