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. 2009 Mar 30;37(10):3354–3366. doi: 10.1093/nar/gkp210

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© 2009

The Author(s) This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 8. — Comparison of operator sequences in Esp1396I. C.Esp1396I binding sites at the CR promoter (proximal, O_R; distal, O_L) and the M promoter (O_M) are aligned. Indicated in yellow are the sites where at least 2/3 of the sequences are identical, seven of which (red lettering) are found in all three. A symmetrical consensus sequence is shown below, closely matching the O_M site. Bases identified from the crystal structure as being involved in DNA–protein interactions are indicated in blue; other symmetrical bases likely to interact with helix 3 of the protein are shown in magenta.