Table 1.

Anti-Candida activity of analogs of 1: disk diffusion assays.

Zones of inhibition. mm @ 300μg/diska
Cmpd.	C. albicansc	C. glabrata	C. krusei	C. albicansd,e	C. albicanse
1b	50	15	35	15	50
14a	10	0	9	9	9
14b	8	7.5	0	0	7.5
14c	13	10	9	12	17
14d	7.5	0	6.5	8	9
14e	8	7.5	7.5	0	8
14f	8	7	0	0	7
14g	0	0	0	0	0
14h	8	7	11	10	12
15a	10	0	9	12	12
15d	10	0	7.5	8	8
15g	0	0	0	0	0
15h	9	10	8	12	–
16	8	0	7	0	–
18a,c,g	0	0	0	0	0
19a,g	0	0	0	0	0
20a	10	0	9	0	0
20b	8	0	0	0	0
AmBf	22	19	15	12	23

^aSabouraud agar. “–”, not tested.

^b10 μg/disk.

^cATCC 14503,

^d96–489, patient isolate, Ref. 9b,

^eUCDFR1, fluconazole-resistant (MIC >32 μg/mL), see Ref. 9b.

^fAmB, amphotericin B (5 μg/disk).