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. 2009 Jun 15;4(6):e5923. doi: 10.1371/journal.pone.0005923

Figure 7. Survival kinetics of M. smegmatis (with M. tuberculosis gyrA-AS and gyrB –AS plasmids individually).

Figure 7

Induction at 10 uM IPTG concentration. In the case of gyrA-AS r-M. smegmatis the cfu reduction is >3 log10 (bactericidal target), but gyrB-AS showed no cfu reduction as the orphan gyrB takes over once the other gyrB transcript is blocked.