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. 2009 Jun 17;4(6):e5903. doi: 10.1371/journal.pone.0005903

Table 3. Clinical characteristics of patients used for measurement of circulating cytokines.

Limited cutaneous SSc Late diffuse cutaneous SSc Early diffuse cutaneous SSc
Number 110 34 33
N females (%) 89 (81) 26 (76) 27 (82)
Age at onset 43.3±8.9 42.7±11.7 41.3±9.8
Disease duration 11.2±7.1 8.1±5.3 1.5±0.8
ANA positivity 100% 77% 92%
Pulmonary hypertension 37% 19% 18%
Lung fibrosis 22% 47% 30%
Current Therapies
MMF 0% 7% 8%
Cyclophosphamide 0% 16% 33%
Prednisolone 14% 11% 23%
Hydroxychloroquine 3% 0% 0%
anti-IL-3 0% 0% 0%
Methotrexate 0% 0% 0%
Tacrolimus 0% 0% 0%