Table 1.

Baseline characteristics of patients enrolled into the CLOTS 1 trial

	Thigh-length GCS (n=1256)	Avoid GCS (n=1262)
Overall
Age (years)*	76 (68–83)	76 (68–83)
Men	620 (49·4%)	622 (49·3%)
Final diagnosis at hospital discharge
Ischaemic stroke	1058 (84·2%)	1087 (86·1%)
Haemorrhagic stroke	132 (10·5%)	100 (7·9%)
Uncertain	39 (3·1%)	38 (3·0%)
Non-strokes (included in primary analysis)	24 (1·9%)	35 (2·8%)
Missing (no discharge form)	3 (0·2%)	2 (0·2%)
Past history and risk factors
Previous DVT or PE	55 (4·4%)	56 (4·4%)
Diabetes	191 (15·2%)	165 (13·1%)
Peripheral vascular disease	36 (2·9%)	26 (2·1%)
Overweight	320 (25·5%)	343 (27·2%)
Cigarette smoker	235 (18·7%)	235 (18·6%)
Independent in daily activities before stroke*	1145 (91·2%)	1152 (91·3%)
Lives alone before stroke*	443 (35·3%)	461 (36·5%)
Indicators of stroke severity
Able to lift both arms off bed*	547 (43·5%)	558 (44·2%)
Able to talk and oriented in time, place, and person*	898 (71·5%)	890 (70·5%)
Able to lift both legs off bed†	542 (43·1%)	550 (43·6%)
Able to walk without help*	0 (0%)	0 (0%)
Prescribed heparin, warfarin, or alteplase at baseline†	98 (7·8%)	109 (8·6%)
Delay since stroke onset to randomisation (0–1days)†	525 (41·8%)	511 (40·5%)
Stroke severity: probability of being alive and independent in daily activities 0–0·15†	660 (52·5%)	684 (54·2%)
Stroke severity: probability of being alive and independent in daily activities	0·14 (0·04–0·38)	0·12 (0·03–0·40)
Compression Doppler ultrasound at 30 days considered unlikely to be practical at time of randomisation	351 (27·9%)	330 (26·1%)

Data are median (IQR) or number (%). GCS=graduated compression stockings. DVT=deep vein thrombosis. PE=pulmonary embolism.

^*Factors included in model to predict probability of being alive and independent at 6 months.²⁰

^†Variables included in minimisation.