. Author manuscript; available in PMC: 2009 Jun 8.

Published in final edited form as: Genesis. 2009 Mar;47(3):188–195. doi: 10.1002/dvg.20476

Table 1.

Cardiovascular and Thymic Phenotype at E18.5

		CVD
	Normal	AoA only	Enlarged V, PT	Abn OFT	VSD	Thymus: hypo/aplasia	Total
COET; Tbx1^Cre^/+	1	4	11	4	6/11	15 (79%)^*	19 (95%)^**
Tbx1^Cre^/+	8	3	-	-	-	1 (9%)	11 (27%)
COET;Tbx1^+/+	18	-	-	-	-	-	18

AoA, aortic arch defects including abnormal origin of right subclavian, interrupted aortic arch; V, PT, ventricle, pulmonary trunk; OFT, outflow tract (includes TGA, DORV and TAC).

Student’s t-test:

P = 0.0002;

^**

P =0.0001.