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Phenotype of Near-Term COET;Tbx1cre/− Animals
| CVD |
Other |
|||||||
|---|---|---|---|---|---|---|---|---|
| TAC | Restore septation | Restore alignment | VSD | Rescue Palate | Rescue Ear | Normal Thymus | Total | |
| COET;Tbx1cre/− | 1 | 5 | 3 | 6 | 6 | 6 | 6 | 6 |
| Tbx1cre/− | 4 | 0 | 0 | 4 | 0 | 0 | 0 | 4 |
TAC, truncus exiting right ventricle. Septated outflow tract in rescued mutants can occur with or without a corresponding improvement in OFT alignment or aortic arch patterning defects.
