Delayed increase in formation [3-13C]lactate (Lac C3) in ipsi and contra sides of brain from young TBI rats at 15, 30 and 60 min after i.p. injection of [1,6-13C]glucose. These time points represent 5h 15 min, 5h 30 min, and 6hr after the TBI injury. Spectra we obtained on PCA extracts of brain as described in methods. Values are mean ± S.E. of data for nmol 13C incorporated/mg protein, from 6 TBI and 5 sham rats at each time point. Data were analyzed using one-way ANOVA. *p<0.05 significant difference between ipsi and contra sides of TBI and sham brain as indicated the horizontal lines over the bars.